1. God is sovereign (23-28)
When Peter and John were threatened and released from prison, they went back to the believers and had a prayer meeting. They began their prayer by acknowledging the sovereignty of the Creator God. They quoted Psalm 118:22, and marveled at how Herod and Pontius Pilate and the Gentiles and Jewish rulers had conspired together against the Messiah, and thus had fulfilled the prophecies of the Psalm. They accepted persecution as a part of God's sovereignty, and they rejoiced in God who rules over all.
2. Enable us to speak with boldness (29-31)
They had just two prayer requests: (i) Lord, consider their threats and enable us to speak your word with boldness; (ii) Lord, stretch out your hand to heal through the name of Jesus. They did not try to save themselves; they only asked to extend God's mercy and love into the lives of sinsick and suffering people.
Application: Lord, grant me boldness to speak your word.
One Word: God is sovereign